Comparison of 3D-conformal and intensity-modulated radiation therapy for left-sided breast cancer

Background: We compared 3D-conformal radiation therapy (3D-CRT) and intensity-modulated (IMRT) planning for left-sided post-mastectomy patients. Aim: To compare the dose coverage of target volume (PTV) delivered to organs at risk (OAR) 3D-CRT IMRT plans. Setting: Department Oncology, central South Africa. Methods: Twenty-six archived CT scans patients with breast cancer were included. The plans designed each patient using Monaco © system (version 5.11.02). Statistical analysis was performed PTV (V 95% , V 98% 105% ) doses heart, ipsilateral lung, combined lungs, contralateral breast, oesophagus. Results: 67.07% 0.21%, respectively, 92.32% 1.10% However, plans’ mean PTV, receiving prescribed (PD), 7.68% 3D-CRT’s 32.93%. resulted in a 22 Gy < 10% value 4.15%. 18.87 45% values lungs 28.09% 13.70%, respectively. showed lower oesophagus (5.07 Gy) 5 15% = 3.51%). Conclusion: It shown that treatment can effectively achieve clinical goals radiotherapy. Contribution: findings underscore continuing relevance oncology optimal low OAR dose.